Chronic Obstructive Pulmonary Disease (COPD)

The COPD/Alpha-1 Link

With more than 12 million Americans currently diagnosed with chronic obstructive pulmonary disease (COPD), and an estimated 12 million yet to be identified, COPD continues to be one of the leading causes of death in the United States1. In fact, the National Heart, Lung, and Blood Institute estimates COPD will be the third leading cause of death in the United States by year 20202.

Some of those currently living with COPD, or even those in which it may develop, could have an underlining genetic disorder leading to their condition. This disorder is called Alpha-1 Antitrypsin Deficiency, or simply Alpha-1, and the American Thoracic Society (ATS) estimates that up to 4.5% of patients with COPD may have severe Alpha-1. The World Health Organization identifies Alpha-1 as one of only three risk factors that can individually cause COPD.

Yet, as much as 95% of the estimated 100,000 individuals having severe Alpha-1 remain undiagnosed or improperly diagnosed. This unsettling statistic does not include carriers of the abnormal Alpha-1 Antitrypsin gene, estimated at 25 million in the United States alone. Studies have shown that even carriers could have an increased risk for lung disease — as much as 18% of COPD patients carry a single copy of the abnormal gene. With an estimated 100,000 Americans having severe Alpha-1, this disorder is more prevalent than cystic fibrosis, tuberculosis and mesothelioma combined3.

COPD Care Program

Apria HealthcareCoram and and its affiliate Apria Healthcare offer the most comprehensive and in-depth program for the treatment of COPD patients — Apria's COPD Care Program. This program is designed to provide both you and your patients the most thorough and complete treatment plan for those living with COPD. As one of the leading Alpha-1 therapy providers, Coram's affiliation with Apria is a testament of our commitment to increasing awareness around this highly prevalent, but underdiagnosed, disease. Through Apria's COPD Care Program, your patients will receive unmatched coordination of care that is tailored to your needs and that of your patients.

Click here to learn more about Apria and their COPD program.


» What is Alpha-1 and why is it important to test for Alpha-1?

 

1 National Heart Lung Blood Institute. Take the First Step to Breathing Better. Learn More About COPD. COPD (Chronic Obstructive Pulmonary Disease). Retrieved September 30, 2010, from http://www.nhlbi.nih.gov/health/public/lung/copd/index.htm
2 Published in Am J Respir Crit Care Med Vol 165. pp 838 -844, 2002. Internet address: www.atsjournals.org
3 de Serres FJ. Alpha-1 antitrypsin deficiency is not a rare disease but a disease that is rarely diagnosed. Environ Health Perspect. 2003;111(16):1851-1854